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Some patients report improvements in: Energy levels Mental clarity Exercise recovery Overall sense of well-being Responses vary, and benefits are not guaranteed, a Risk to Benefit analysis is the best way to approach these therapies

The implication for clinical practice is that restoring youthful MOTS-c signaling might be a mechanistically legitimate target for longevity intervention

150 These breaks pose significant threats to genomic stability and are implicated in the pathology of cancer, neurological disorders, growth retardation, and immune deficiencies

longer-term storage at -20C to -80C depending on institutional standards